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Crystal structure of suboptimal viral fragments of Epstein Barr Virus Rta peptide-HLA complex that stimulate CD8 T cell response

Peptides presented by Human leukocyte antigen (HLA) class-I molecules are generally 8–10 amino acids in length. However, the predominant pool of peptide fragments generated by proteasomes is less than 8 amino acids in length. Using the Epstein - Barr virus (EBV) Rta-epitope (ATIGTAMYK, residues 134–...

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Detalles Bibliográficos
Autores principales: Huan, Xuelu, Zhuo, Ziyi, Xiao, Ziwei, Ren, Ee Chee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853878/
https://www.ncbi.nlm.nih.gov/pubmed/31723204
http://dx.doi.org/10.1038/s41598-019-53201-6