Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model

Nipah virus (NiV) is a pathogenic paramyxovirus and zoononis with very high human fatality rates. Previous protein over-expression studies have shown that various mutations to the common N-terminal STAT1-binding motif of the NiV P, V, and W proteins affected the STAT1-binding ability of these protei...

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Detalles Bibliográficos
Autores principales: Satterfield, Benjamin A., Borisevich, Viktoriya, Foster, Stephanie L., Rodriguez, Sergio E., Cross, Robert W., Fenton, Karla A., Agans, Krystle N., Basler, Christopher F., Geisbert, Thomas W., Mire, Chad E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853903/
https://www.ncbi.nlm.nih.gov/pubmed/31723221
http://dx.doi.org/10.1038/s41598-019-53037-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853903/
https://www.ncbi.nlm.nih.gov/pubmed/31723221
http://dx.doi.org/10.1038/s41598-019-53037-0

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