In vitro study of interaction of 17β-hydroxysteroid dehydrogenase type 10 and cyclophilin D and its potential implications for Alzheimer’s disease

In early stages of Alzheimer’s disease (AD), amyloid-β (Aβ) accumulates in neuronal mitochondria where it interacts with a number of biomolecules including 17beta-hydroxysteroide dehydrogenase 10 (17β-HSD10) and cyclophilin D (cypD). It has been hypothesized that 17β-HSD10 interacts with cypD preven...

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Detalles Bibliográficos
Autores principales: Hemmerová, Erika, Špringer, Tomáš, Krištofiková, Zdenka, Homola, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853915/
https://www.ncbi.nlm.nih.gov/pubmed/31723183
http://dx.doi.org/10.1038/s41598-019-53157-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853915/
https://www.ncbi.nlm.nih.gov/pubmed/31723183
http://dx.doi.org/10.1038/s41598-019-53157-7

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