Comparative muscle irritation and pharmacokinetics of florfenicol-hydroxypropyl-β-cyclodextrin inclusion complex freeze-dried powder injection and florfenicol commercial injection in beagle dogs

Florfenicol (FF) is a novel animal-specific amidohydrin broad-spectrum antibiotic. However, its aqueous solubility is extremely poor, far below the effective dose required for veterinary clinic. Thus, FF is often used in large doses, which significantly limits its preparation and application. To ove...

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Detalles Bibliográficos
Autores principales: Fan, Guoqing, Zhang, Li, Shen, Yun, Shu, Gang, Yuan, Zhixiang, Lin, Juchun, Zhang, Wei, Peng, Guangneng, Zhong, Zhijun, Yin, Lizi, Fu, Hualin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853948/
https://www.ncbi.nlm.nih.gov/pubmed/31723173
http://dx.doi.org/10.1038/s41598-019-53304-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853948/
https://www.ncbi.nlm.nih.gov/pubmed/31723173
http://dx.doi.org/10.1038/s41598-019-53304-0

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