MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis

The MUC4 membrane-bound mucin is a large O-glycoprotein involved in epithelial homeostasis. At the cancer cell surface MUC4 interacts with ErbB2 receptor via EGF domains to promote cell proliferation and migration. MUC4 is highly regarded as a therapeutic target in pancreatic cancer as it is not exp...

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Detalles Bibliográficos
Autores principales: Liberelle, Maxime, Magnez, Romain, Thuru, Xavier, Bencheikh, Yamina, Ravez, Severine, Quenon, Camille, Drucbert, Anne-Sophie, Foulon, Catherine, Melnyk, Patricia, Seuningen, Isabelle Van, Lebègue, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853952/
https://www.ncbi.nlm.nih.gov/pubmed/31723153
http://dx.doi.org/10.1038/s41598-019-53099-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853952/
https://www.ncbi.nlm.nih.gov/pubmed/31723153
http://dx.doi.org/10.1038/s41598-019-53099-0

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