Mechanisms of GABA(B) receptor enhancement of extrasynaptic GABA(A) receptor currents in cerebellar granule cells

Many neurons, including cerebellar granule cells, exhibit a tonic GABA current mediated by extrasynaptic GABA(A) receptors. This current is a critical regulator of firing and the target of many clinically relevant compounds. Using a combination of patch clamp electrophysiology and photolytic uncagin...

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Detalles Bibliográficos
Autores principales: Khatri, Shailesh N., Wu, Wan-Chen, Yang, Ying, Pugh, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853962/
https://www.ncbi.nlm.nih.gov/pubmed/31723152
http://dx.doi.org/10.1038/s41598-019-53087-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853962/
https://www.ncbi.nlm.nih.gov/pubmed/31723152
http://dx.doi.org/10.1038/s41598-019-53087-4

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