Loss of Mob1a/b impairs the differentiation of mouse embryonic stem cells into the three germ layer lineages

The Hippo pathway plays a crucial role in cell proliferation and apoptosis and can regulate stem cell maintenance and embryonic development. MOB kinase activators 1A and 1B (Mob1a/b) are key components of the Hippo pathway, whose homozygous deletion in mice causes early embryonic lethality at the pr...

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Detalles Bibliográficos
Autores principales: Bae, June Sung, Kim, Sun Mi, Jeon, Yoon, Sim, Juyeon, Jang, Ji Yun, Son, Jaehyung, Hong, Woosol, Park, Mi Kyung, Lee, Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853965/
https://www.ncbi.nlm.nih.gov/pubmed/31723125
http://dx.doi.org/10.1038/s12276-019-0342-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853965/
https://www.ncbi.nlm.nih.gov/pubmed/31723125
http://dx.doi.org/10.1038/s12276-019-0342-z

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