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Coadministration of lithium and celecoxib reverses manic-like behavior and decreases oxidative stress in a dopaminergic model of mania induced in rats

The present study intends to investigate the effect of lithium (Li) and celecoxib (Cel) coadministration on the behavioral status and oxidative stress parameters in a rat model of mania induced by dextroamphetamine (d-AMPH). Male Wistar rats were treated with d-AMPH or saline (Sal) for 14 days; on t...

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Detalles Bibliográficos
Autores principales: Valvassori, Samira S., Tonin, Paula T., Dal-Pont, Gustavo C., Varela, Roger B., Cararo, José Henrique, Garcia, Abel Freitas, Gava, Fernanda F., Menegas, Samira, Soares, Jair C., Quevedo, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853972/
https://www.ncbi.nlm.nih.gov/pubmed/31723123
http://dx.doi.org/10.1038/s41398-019-0637-9