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The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis

RNA has been classically known to play central roles in biology, including maintaining telomeres, protein synthesis, and in sex chromosome compensation. While thousands of long noncoding RNAs (lncRNAs) have been identified, attributing RNA-based roles to lncRNA loci requires assessing whether phenot...

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Detalles Bibliográficos
Autores principales: Lewandowski, Jordan P., Lee, James C., Hwang, Taeyoung, Sunwoo, Hongjae, Goldstein, Jill M., Groff, Abigail F., Chang, Nydia P., Mallard, William, Williams, Adam, Henao-Meija, Jorge, Flavell, Richard A., Lee, Jeannie T., Gerhardinger, Chiara, Wagers, Amy J., Rinn, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853988/
https://www.ncbi.nlm.nih.gov/pubmed/31723143
http://dx.doi.org/10.1038/s41467-019-12970-4