Mechanisms Underlying the Anti-inflammatory and Immunosuppressive Activity of Ruxolitinib

The JAK-STAT signaling pathway plays a central role in signal transduction in hematopoietic cells, as well as in cells of the immune system. The occurrence in most patients affected by myeloproliferative neoplasms (MPNs) of driver mutations resulting in the constitutive activation of JAK2-dependent...

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Detalles Bibliográficos
Autores principales: Elli, Elena Maria, Baratè, Claudia, Mendicino, Francesco, Palandri, Francesca, Palumbo, Giuseppe Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854013/
https://www.ncbi.nlm.nih.gov/pubmed/31788449
http://dx.doi.org/10.3389/fonc.2019.01186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854013/
https://www.ncbi.nlm.nih.gov/pubmed/31788449
http://dx.doi.org/10.3389/fonc.2019.01186

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