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Cell Wall-Associated Virulence Factors Contribute to Increased Resilience of Old Cryptococcus neoformans Cells

As Cryptococcus neoformans mother cells generationally age, their cell walls become thicker and cell-wall associated virulence factors are upregulated. Antiphagocytic protein 1 (App1), and laccase enzymes (Lac1 and Lac2) are virulence factors known to contribute to virulence of C. neoformans during...

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Detalles Bibliográficos
Autores principales: Orner, Erika P., Bhattacharya, Somanon, Kalenja, Klea, Hayden, Danielle, Del Poeta, Maurizio, Fries, Bettina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854031/
https://www.ncbi.nlm.nih.gov/pubmed/31787940
http://dx.doi.org/10.3389/fmicb.2019.02513