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Mitoautophagy: A Unique Self-Destructive Path Mitochondria of Upper Motor Neurons With TDP-43 Pathology Take, Very Early in ALS

Mitochondrial dysfunction is one of the converging paths for many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), and TDP-43 pathology is the most common proteinopathy detected in ALS and ALS/Frontotemporal lobar degeneration (ALS/FTLD). We recently identified mitochondria...

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Detalles Bibliográficos
Autores principales: Gautam, Mukesh, Xie, Edward F., Kocak, Nuran, Ozdinler, P. Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854036/
https://www.ncbi.nlm.nih.gov/pubmed/31787882
http://dx.doi.org/10.3389/fncel.2019.00489