Involvement of Phosphatase and Tensin Homolog in Cyclin-Dependent Kinase 4/6 Inhibitor-Induced Blockade of Glioblastoma

Dysregulation of retinoblastoma (Rb) signaling pathway have been established as a requirement for glioblastoma (GBM) initiation and progression, which suggests that blockade of CDK4/6-Rb signaling axis for GBM treatment. Palbociclib, a selective inhibitor of the cyclin-dependent kinases CDK4/6, has...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Songlin, Yuan, Dun, Li, Yifeng, Qi, Qi, Guo, Bingzhong, Yang, Shun, Zhou, Jilin, Xu, Lu, Chen, Tiange, Yang, Chenxing, Liu, Junyu, Li, Buyan, Yao, Li, Jiang, Weixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854038/
https://www.ncbi.nlm.nih.gov/pubmed/31787897
http://dx.doi.org/10.3389/fphar.2019.01316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854038/
https://www.ncbi.nlm.nih.gov/pubmed/31787897
http://dx.doi.org/10.3389/fphar.2019.01316

Ejemplares similares