Kinesin-5 Is Dispensable for Bipolar Spindle Formation and Elongation in Candida albicans, but Simultaneous Loss of Kinesin-14 Activity Is Lethal

Mitotic spindles assume a bipolar architecture through the concerted actions of microtubules, motors, and cross-linking proteins. In most eukaryotes, kinesin-5 motors are essential to this process, and cells will fail to form a bipolar spindle without kinesin-5 activity. Remarkably, inactivation of...

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Detalles Bibliográficos
Autores principales: Shoukat, Irsa, Frazer, Corey, Allingham, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854041/
https://www.ncbi.nlm.nih.gov/pubmed/31722992
http://dx.doi.org/10.1128/mSphere.00610-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854041/
https://www.ncbi.nlm.nih.gov/pubmed/31722992
http://dx.doi.org/10.1128/mSphere.00610-19

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