Increased Mosquito Midgut Infection by Dengue Virus Recruitment of Plasmin Is Blocked by an Endogenous Kazal-type Inhibitor

Dengue symptoms include alteration of blood coagulation and fibrinolysis, causing severe hemorrhage and death. Here, we demonstrate that higher concentration of plasmin, the human fibrinolytic factor, in blood meal enhances dengue virus (DENV) infection in mosquito midgut and dissemination in mosqui...

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Detalles Bibliográficos
Autores principales: Ramesh, Karthik, Walvekar, Varsha A., Wong, Benjamin, Sayed, Ahmed Mahmoud Mohammed, Missé, Dorothée, Kini, R. Manjunatha, Mok, Yu Keung, Pompon, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854080/
https://www.ncbi.nlm.nih.gov/pubmed/31726374
http://dx.doi.org/10.1016/j.isci.2019.10.056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854080/
https://www.ncbi.nlm.nih.gov/pubmed/31726374
http://dx.doi.org/10.1016/j.isci.2019.10.056

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