The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells

Apoptosis of endothelial cells is a very important event in various diseases and angiogenesis. We recently reported that ras guanyl nucleotide releasing protein 2 (RasGRP2), which is a guanine nucleotide exchange factor, was expressed in the human umbilical vein endothelial cells (HUVECs) and that R...

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Detalles Bibliográficos
Autores principales: Takino, Jun-ichi, Sato, Takuma, Nagamine, Kentaro, Hori, Takamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854084/
https://www.ncbi.nlm.nih.gov/pubmed/31723205
http://dx.doi.org/10.1038/s41598-019-53419-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854084/
https://www.ncbi.nlm.nih.gov/pubmed/31723205
http://dx.doi.org/10.1038/s41598-019-53419-4

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