Downregulation of miR-199a-3p mediated by the CtBP2-HDAC1-FOXP3 transcriptional complex contributes to acute lung injury by targeting NLRP1

Emerging evidence indicates that microRNAs (miRNAs) play fundamental roles in the pathogenesis of multiple diseases, including acute lung injury (ALI). Here, we discovered that miR-199a-3p was significantly downregulated in ALI lung tissues using a microarray analysis. In vitro lipopolysaccharide (L...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Dong, Wei-Hua, Chen, Qiang, Li, Qiu-Gen, Qiu, Zhong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854378/
https://www.ncbi.nlm.nih.gov/pubmed/31754335
http://dx.doi.org/10.7150/ijbs.37133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854378/
https://www.ncbi.nlm.nih.gov/pubmed/31754335
http://dx.doi.org/10.7150/ijbs.37133

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