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Comprehensive Interactome Analysis Reveals that STT3B Is Required for N-Glycosylation of Lassa Virus Glycoprotein

Lassa virus (LASV) is the causative agent of a fatal hemorrhagic fever in humans. The glycoprotein (GP) of LASV mediates viral entry into host cells, and correct processing and modification of GP by host factors is a prerequisite for virus replication. Here, using an affinity purification-coupled ma...

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Detalles Bibliográficos
Autores principales: Zhu, Shenglin, Wan, Weiwei, Zhang, Yanjun, Shang, Weijuan, Pan, Xiaoyan, Zhang, Lei-Ke, Xiao, Gengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854512/
https://www.ncbi.nlm.nih.gov/pubmed/31511384
http://dx.doi.org/10.1128/JVI.01443-19