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High glucose inhibits osteogenic differentiation and proliferation of MC3T3-E1 cells by regulating P2X7

Diabetes mellitus adversely affects human bones and increases the risk of developing osteoporosis. In the present study, treatment with 30 mmol/l glucose was used to establish a high glucose (HG) cell model in vitro. Plasmids were used to overexpress the P2X purinoceptor 7 (P2X7) gene. Brilliant blu...

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Detalles Bibliográficos
Autores principales: Yang, Jinsan, Ma, Cao, Zhang, Maoshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854521/
https://www.ncbi.nlm.nih.gov/pubmed/31702818
http://dx.doi.org/10.3892/mmr.2019.10790