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Placental growth factor gene silencing mitigates the epithelial-to-mesenchymal transition via the p38 MAPK pathway in rats with hyperoxia-induced lung injury

Hyperoxia may cause pulmonary fibrosis in neonates and is characterized by the epithelial-to-mesenchymal transition (EMT) of alveolar epithelial cells. The placental growth factor (PLGF) gene is a member of the vascular endothelial growth factor family and is highly expressed in lung tissues that ha...

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Detalles Bibliográficos
Autores principales: Zhao, Shuang, Luo, Gang, Wu, Hongmin, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854522/
https://www.ncbi.nlm.nih.gov/pubmed/31702808
http://dx.doi.org/10.3892/mmr.2019.10785