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miR-21-5p ameliorates hyperoxic acute lung injury and decreases apoptosis of AEC II cells via PTEN/AKT signaling in rats

Inhibiting apoptosis of type II alveolar epithelial cells (AEC II) is an effective way to decrease hyperoxic acute lung injury (HALI); however, the specific underlying molecular mechanisms have not yet been fully elucidated. Although miRNA-21-5p has previously been reported to decrease H(2)O(2)-indu...

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Detalles Bibliográficos
Autores principales: Qin, Song, Wang, Hongliang, Liu, Guoyue, Mei, Hong, Chen, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854583/
https://www.ncbi.nlm.nih.gov/pubmed/31702805
http://dx.doi.org/10.3892/mmr.2019.10779