CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells

Angiogenesis can produce an invasive and destructive front, also named a pannus, comprised of inflammatory vascular tissue that covers and erodes articular cartilage, subchondral bone and peri-articular soft tissues in rheumatoid arthritis (RA). Paeoniflorin-6′-O-benzene sulfonate (CP-25) is a novel...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Gao, Mei, Chen, Jinyu, Song, Lihua, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854590/
https://www.ncbi.nlm.nih.gov/pubmed/31661133
http://dx.doi.org/10.3892/mmr.2019.10765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854590/
https://www.ncbi.nlm.nih.gov/pubmed/31661133
http://dx.doi.org/10.3892/mmr.2019.10765

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