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Estrogen receptor α (ERα) indirectly induces transcription of human renal organic anion transporter 1 (OAT1)
Organic anion transporter 1 (OAT1) is a polyspecific transport protein located in the basolateral membrane of renal proximal tubule cells. OAT1 plays a pivotal role in drug clearance. Adverse drug reactions (ADR) are observed more frequently in women than in men, especially ADR are higher in women f...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854606/ https://www.ncbi.nlm.nih.gov/pubmed/31724834 http://dx.doi.org/10.14814/phy2.14229 |