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Transcriptional profiling predicts running promotes cerebrovascular remodeling in young but not midlife mice

BACKGROUND: The incidence of dementia and cognitive decline is increasing with no therapy or cure. One of the reasons treatment remains elusive is because there are various pathologies that contribute to age-related cognitive decline. Specifically, with Alzheimer’s disease, targeting to reduce amylo...

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Detalles Bibliográficos
Autores principales: Foley, Kate E., Yang, Hongtian Stanley, Graham, Leah C., Howell, Gareth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854620/
https://www.ncbi.nlm.nih.gov/pubmed/31726991
http://dx.doi.org/10.1186/s12864-019-6230-z