CRISPR/Cas9-mediated knockout of NSD1 suppresses the hepatocellular carcinoma development via the NSD1/H3/Wnt10b signaling pathway

BACKGROUND: The NSD family of histone lysine methyltransferases have emerged as important biomarkers that participate in a variety of malignancies. Recent evidence has indicated that somatic dysregulation of the nuclear receptor binding SET domain-containing protein 1 (NSD1) is associated with the t...

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Detalles Bibliográficos
Autores principales: Zhang, Shuhua, Zhang, Fan, Chen, Qing, Wan, Chidan, Xiong, Jun, Xu, Jianqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854717/
https://www.ncbi.nlm.nih.gov/pubmed/31727171
http://dx.doi.org/10.1186/s13046-019-1462-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854717/
https://www.ncbi.nlm.nih.gov/pubmed/31727171
http://dx.doi.org/10.1186/s13046-019-1462-y

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