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Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

BACKGROUND: Sepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived suppressor cells (MDSCs), which have been demonstrated to...

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Detalles Bibliográficos
Autores principales: Hollen, McKenzie K., Stortz, Julie A., Darden, Dijoia, Dirain, Marvin L., Nacionales, Dina C., Hawkins, Russell B., Cox, Michael C., Lopez, Maria-Cecilia, Rincon, Jaimar C., Ungaro, Ricardo, Wang, Zhongkai, Wu, Quran, Brumback, Babette, Gauthier, Marie-Pierre L., Kladde, Michael, Leeuwenburgh, Christiaan, Segal, Mark, Bihorac, Azra, Brakenridge, Scott, Moore, Frederick A., Baker, Henry V., Mohr, Alicia M., Moldawer, Lyle L., Efron, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854728/
https://www.ncbi.nlm.nih.gov/pubmed/31722736
http://dx.doi.org/10.1186/s13054-019-2628-x