m(6)A modification suppresses ocular melanoma through modulating HINT2 mRNA translation

BACKGROUND: Dynamic N(6)-methyladenosine (m(6)A) RNA modification generated and erased by N(6)-methyltransferases and demethylases regulates gene expression, alternative splicing and cell fate. Ocular melanoma, comprising uveal melanoma (UM) and conjunctival melanoma (CM), is the most common primary...

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Detalles Bibliográficos
Autores principales: Jia, Ruobing, Chai, Peiwei, Wang, Shanzheng, Sun, Baofa, Xu, Yangfan, Yang, Ying, Ge, Shengfang, Jia, Renbing, Yang, Yun-Gui, Fan, Xianqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854757/
https://www.ncbi.nlm.nih.gov/pubmed/31722709
http://dx.doi.org/10.1186/s12943-019-1088-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854757/
https://www.ncbi.nlm.nih.gov/pubmed/31722709
http://dx.doi.org/10.1186/s12943-019-1088-x

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