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iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis

INTRODUCTION: A pivotal effect of lymphatic vessel (LV) function in joint homeostasis was identified in the tumor necrosis factor-transgenic (TNF-Tg) mouse model of rheumatoid arthritis (RA). Specifically, loss of LV contractions is associated with progressive synovitis and erosions. Furthermore, dr...

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Detalles Bibliográficos
Autores principales: Bell, Richard D., Slattery, Pamelia N., Wu, Emily K., Xing, Lianping, Ritchlin, Christopher T., Schwarz, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854801/
https://www.ncbi.nlm.nih.gov/pubmed/31727153
http://dx.doi.org/10.1186/s13075-019-2039-z