The influence of PFK-II overexpression on neuroblastoma patients’ survival may be dependent on the particular isoenzyme expressed, PFKFB3 or PFKFB4

BACKGROUND/AIM: During cancer progression metabolic reprogramming is observed in parallel to the alternation in transcriptional profiles of malignant cells. Recent studies suggest that metabolic isoenzymes of phosphofructokinase II (PFK-II) – PFKFB3 and PFKFB4, often induced in hypoxic environment,...

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Detalles Bibliográficos
Autores principales: Trojan, Sonia E., Markiewicz, Michał J., Leśkiewicz, Katarzyna, Kocemba-Pilarczyk, Kinga A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854802/
https://www.ncbi.nlm.nih.gov/pubmed/31754349
http://dx.doi.org/10.1186/s12935-019-1005-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854802/
https://www.ncbi.nlm.nih.gov/pubmed/31754349
http://dx.doi.org/10.1186/s12935-019-1005-9

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