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Structure and Dynamics of Cinnamycin–Lipid Complexes: Mechanisms of Selectivity for Phosphatidylethanolamine Lipids

[Image: see text] Cinnamycin is a lantibiotic peptide, which selectively binds to and permeabilizes membranes containing phosphatidylethanolamine (PE) lipids. As PE is a major component of many bacterial cell membranes, cinnamycin has considerable potential for destroying these. In this study, molec...

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Detalles Bibliográficos
Autores principales: Vestergaard, Mikkel, Berglund, Nils Anton, Hsu, Pin-Chia, Song, Chen, Koldsø, Heidi, Schiøtt, Birgit, Sansom, Mark S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854821/
https://www.ncbi.nlm.nih.gov/pubmed/31737850
http://dx.doi.org/10.1021/acsomega.9b02949