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lptG contributes to changes in membrane permeability and the emergence of multidrug hypersusceptibility in a cystic fibrosis isolate of Pseudomonas aeruginosa

PURPOSE: In the lungs of cystic fibrosis patients, Pseudomonas aeruginosa is exposed to a myriad of antibiotics leading to alterations in antibiotic susceptibility. This study identifies mutations resulting in hypersusceptibility in isogenic mutants of a P. aeruginosa clinical isolate, PA34. METHODS...

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Detalles Bibliográficos
Autores principales: Harrison, Lucas B., Fowler, Randal C., Abdalhamid, Baha, Selmecki, Anna, Hanson, Nancy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854846/
https://www.ncbi.nlm.nih.gov/pubmed/30977288
http://dx.doi.org/10.1002/mbo3.844