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Single mutations in BraRS confer high resistance against nisin A in Staphylococcus aureus

Nisin A is a lantibiotic produced by Lactococcus lactis that is widely used as a food preservative. In Staphylococcus aureus, the BraRS two‐component system (TCS) senses nisin A and regulates the expression of the ABC transporter VraDE, which is responsible for nisin A resistance. In this study, we...

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Detalles Bibliográficos
Autores principales: Arii, Kaoru, Kawada‐Matsuo, Miki, Oogai, Yuichi, Noguchi, Kazuyuki, Komatsuzawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854852/
https://www.ncbi.nlm.nih.gov/pubmed/30656859
http://dx.doi.org/10.1002/mbo3.791