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Insights into pancreatic β cell energy metabolism using rodent β cell models

Background: Mitochondrial diabetes is primarily caused by β-cell failure, a cell type whose unique properties are important in pathogenesis. Methods: By reducing glucose, we induced energetic stress in two rodent β-cell models to assess effects on cellular function. Results: Culturing rat insulin-se...

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Detalles Bibliográficos
Autores principales: Morten, Karl J, Potter, Michelle, Badder, Luned, Sivathondan, Pamela, Dragovic, Rebecca, Neumann, Abigale, Gavin, James, Shrestha, Roshan, Reilly, Svetlana, Phadwal, Kanchan, Lodge, Tiffany A., Borzychowski, Angela, Cookson, Sharon, Mitchell, Corey, Morovat, Alireza, Simon, Anna Katharina, Uusimaa, Johanna, Hynes, James, Poulton, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854877/
https://www.ncbi.nlm.nih.gov/pubmed/31754635
http://dx.doi.org/10.12688/wellcomeopenres.10535.3