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Insights into pancreatic β cell energy metabolism using rodent β cell models
Background: Mitochondrial diabetes is primarily caused by β-cell failure, a cell type whose unique properties are important in pathogenesis. Methods: By reducing glucose, we induced energetic stress in two rodent β-cell models to assess effects on cellular function. Results: Culturing rat insulin-se...
Autores principales: | Morten, Karl J, Potter, Michelle, Badder, Luned, Sivathondan, Pamela, Dragovic, Rebecca, Neumann, Abigale, Gavin, James, Shrestha, Roshan, Reilly, Svetlana, Phadwal, Kanchan, Lodge, Tiffany A., Borzychowski, Angela, Cookson, Sharon, Mitchell, Corey, Morovat, Alireza, Simon, Anna Katharina, Uusimaa, Johanna, Hynes, James, Poulton, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854877/ https://www.ncbi.nlm.nih.gov/pubmed/31754635 http://dx.doi.org/10.12688/wellcomeopenres.10535.3 |
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