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Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli

BACKGROUND: IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN. METHODS: In the present study we used mass spectrometry-based proteomics in order to quant...

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Detalles Bibliográficos
Autores principales: Paunas, Flavia Teodora Ioana, Finne, Kenneth, Leh, Sabine, Osman, Tarig Al-Hadi, Marti, Hans-Peter, Berven, Frode, Vikse, Bjørn Egil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854890/
https://www.ncbi.nlm.nih.gov/pubmed/31726998
http://dx.doi.org/10.1186/s12882-019-1598-1