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Melittin Inducing the Apoptosis of Renal Tubule Epithelial Cells through Upregulation of Bax/Bcl-2 Expression and Activation of TNF-α Signaling Pathway

BACKGROUND: Acute kidney injury (AKI) caused by bee stings is common, with characteristics of acute onset, severe illness, and high mortality. Melittin, a major component of bee venom, has been considered to play a key role in bee sting related AKI. This study aims to illustrate whether melittin cou...

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Detalles Bibliográficos
Autores principales: Shu, Ying, Yang, Yingying, Zhao, Yuliang, Ma, Liang, Fu, Ping, Wei, Tiantian, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854966/
https://www.ncbi.nlm.nih.gov/pubmed/31772938
http://dx.doi.org/10.1155/2019/9450368