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Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes

BACKGROUND: Organ injury and dysfunction in sepsis accounts for significant morbidity and mortality. Adaptive cellular responses in the setting of sepsis prevent injury and allow for organ recovery. We and others have shown that part of the adaptive response includes regulation of cellular respirati...

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Detalles Bibliográficos
Autores principales: Cyr, Anthony, Chambers, Lauran, Waltz, Paul K., Whelan, Sean P., Kohut, Lauryn, Carchman, Evie, Dyer, Mitchell, Luciano, Jason, Kautza, Benjamin, Gomez, Hernando D., Otterbein, Leo E., Rosengart, Matthew R., Shiva, Sruti, Zuckerbraun, Brian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854992/
https://www.ncbi.nlm.nih.gov/pubmed/31772705
http://dx.doi.org/10.1155/2019/4745067