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Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes
BACKGROUND: Organ injury and dysfunction in sepsis accounts for significant morbidity and mortality. Adaptive cellular responses in the setting of sepsis prevent injury and allow for organ recovery. We and others have shown that part of the adaptive response includes regulation of cellular respirati...
Autores principales: | Cyr, Anthony, Chambers, Lauran, Waltz, Paul K., Whelan, Sean P., Kohut, Lauryn, Carchman, Evie, Dyer, Mitchell, Luciano, Jason, Kautza, Benjamin, Gomez, Hernando D., Otterbein, Leo E., Rosengart, Matthew R., Shiva, Sruti, Zuckerbraun, Brian S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854992/ https://www.ncbi.nlm.nih.gov/pubmed/31772705 http://dx.doi.org/10.1155/2019/4745067 |
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