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Identification of Key Pathways and Genes in the Orai2 Mediated Classical and Mesenchymal Subtype of Glioblastoma by Bioinformatic Analyses

BACKGROUND: Ca(2+) release-activated Ca(2+) channels (CRAC) are the main Ca(2+) entry pathway regulating intracellular Ca(2+) concentration in a variety of cancer types. Orai2 is the main pore-forming subunit of CRAC channels in central neurons. To explore the role of Orai2 in glioblastoma (GBM), we...

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Detalles Bibliográficos
Autores principales: Yuan, Feng, Yi, Li, Hai, Long, Wang, Yingshuai, Yang, Yihan, Li, Tao, Tong, Luqing, Ma, Haiwen, Liu, Peidong, Ming, Haolang, Ren, Bingcheng, Yu, Shengping, Lin, Yu, Yang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855003/
https://www.ncbi.nlm.nih.gov/pubmed/31772693
http://dx.doi.org/10.1155/2019/7049294