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rBMSC/Cav-1(F92A) Mediates Oxidative Stress in PAH Rat by Regulating SelW/14-3-3η and CA1/Kininogen Signal Transduction

BACKGROUND/OBJECTIVES: Carbonic anhydrase 1 (CA1)/kininogen and selenoprotein W (SelW)/14-3-3η signal transduction orchestrate oxidative stress, which can also be regulated by nitric oxide (NO). The mutated caveolin-1 (Cav-1(F92A)) gene may enhance NO production. This study explored the effect of Ca...

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Detalles Bibliográficos
Autores principales: Yu, Wan-cheng, Chen, Hai-ying, Yang, Hong-li, Xia, Peng, Zou, Cheng-wei, Sun, Tong-wen, Wang, Le-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855026/
https://www.ncbi.nlm.nih.gov/pubmed/31781243
http://dx.doi.org/10.1155/2019/6768571