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The Application of CA and PCA to the Evaluation of Lipophilicity and Physicochemical Properties of Tetracyclic Diazaphenothiazine Derivatives

The subject of the study was 11 new synthetized tetracyclic diazaphenothiazine derivatives. Using thin-layer chromatography in a reverse phase system (RP-TLC), their R(M0) lipophilicity parameter was determined. The mobile phase was composed of 0.2 M Tris buffer (pH = 7.4) and acetone (POCH S.A., Gl...

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Detalles Bibliográficos
Autores principales: Nycz–Empel, Anna, Bober, Katarzyna, Wyszomirski, Mirosław, Kisiel, Ewa, Zięba, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855085/
https://www.ncbi.nlm.nih.gov/pubmed/31781473
http://dx.doi.org/10.1155/2019/8131235