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miR-21 regulates vascular smooth muscle cell function in arteriosclerosis obliterans of lower extremities through AKT and ERK1/2 pathways

INTRODUCTION: Arteriosclerosis obliterans (ASO) is a disease that affects the lower extremities. The mechanism of ASO is associated with the proliferation and migration of vascular smooth muscle cells (VSMCs). miR-21 plays a key role in various biological processes of the cardiovascular system, asso...

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Detalles Bibliográficos
Autores principales: Huang, Shuichuan, Xu, Tuo, Huang, Xianying, Li, Siyi, Qin, Wenyi, Chen, Weijie, Zhang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855157/
https://www.ncbi.nlm.nih.gov/pubmed/31749878
http://dx.doi.org/10.5114/aoms.2018.78885