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Aldosterone nongenomically induces angiotensin II receptor dimerization in rat kidney: role of mineralocorticoid receptor and NADPH oxidase

INTRODUCTION: Previous in vitro studies demonstrated that aldosterone nongenomically induces transglutaminase (TG) and reactive oxygen species (ROS), which enhanced angiotensin II receptor (ATR) dimerization. There are no in vivo data in the kidney. MATERIAL AND METHODS: Male Wistar rats were intrap...

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Detalles Bibliográficos
Autores principales: Sinphitukkul, Kittisak, Manotham, Krissanapong, Eiam-Ong, Somchai, Eiam-Ong, Somchit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855162/
https://www.ncbi.nlm.nih.gov/pubmed/31749889
http://dx.doi.org/10.5114/aoms.2019.87135