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Design, Preparation, and Characterization of Novel Calix[4]arene Bioactive Carrier for Antitumor Drug Delivery

An amphiphilic and bioactive calix[4]arene derivative 8 (CA) is designed and successfully synthesized from tert-butyl calix[4] arene 1 by sequential inverse F-C alkylation, nitration, O-alkylation, esterification, aminolysis, reduction, and acylation reaction. The blank micelles of FA-CA and doxorub...

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Detalles Bibliográficos
Autores principales: An, Lin, Wang, Jia-wei, Liu, Jia-dong, Zhao, Zi-ming, Song, Yuan-jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855266/
https://www.ncbi.nlm.nih.gov/pubmed/31788467
http://dx.doi.org/10.3389/fchem.2019.00732