Cargando…

Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders

Evidence from multiple laboratories has accumulated to show that mosaic neuronal aneuploidy and consequent apoptosis characterizes and may underlie neuronal loss in many neurodegenerative diseases, particularly Alzheimer’s disease and frontotemporal dementia. Furthermore, several neurodevelopmental...

Descripción completa

Detalles Bibliográficos
Autores principales: Potter, Huntington, Chial, Heidi J., Caneus, Julbert, Elos, Mihret, Elder, Nina, Borysov, Sergiy, Granic, Antoneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855267/
https://www.ncbi.nlm.nih.gov/pubmed/31788001
http://dx.doi.org/10.3389/fgene.2019.01092