Transcriptional Mutagenesis Prevents Ribosomal DNA Deterioration: The Role of Duplications and Deletions

Clashes between transcription and replication complexes can cause point mutations and chromosome rearrangements on heavily transcribed genes. In eukaryotic ribosomal RNA genes, the system that prevents transcription–replication conflicts also causes frequent copy number variation. Such fast mutation...

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Detalles Bibliográficos
Autores principales: Colizzi, Enrico Sandro, Hogeweg, Paulien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855279/
https://www.ncbi.nlm.nih.gov/pubmed/31651950
http://dx.doi.org/10.1093/gbe/evz235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855279/
https://www.ncbi.nlm.nih.gov/pubmed/31651950
http://dx.doi.org/10.1093/gbe/evz235

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