HCMV miR-US22 down-regulation of EGR-1 regulates CD34+ hematopoietic progenitor cell proliferation and viral reactivation

Reactivation of latent Human Cytomegalovirus (HCMV) in CD34(+) hematopoietic progenitor cells (HPCs) is closely linked to hematopoiesis. Viral latency requires maintenance of the progenitor cell quiescence, while reactivation initiates following mobilization of HPCs to the periphery and differentiat...

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Detalles Bibliográficos
Autores principales: Mikell, Iliyana, Crawford, Lindsey B., Hancock, Meaghan H., Mitchell, Jennifer, Buehler, Jason, Goodrum, Felicia, Nelson, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855405/
https://www.ncbi.nlm.nih.gov/pubmed/31725809
http://dx.doi.org/10.1371/journal.ppat.1007854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855405/
https://www.ncbi.nlm.nih.gov/pubmed/31725809
http://dx.doi.org/10.1371/journal.ppat.1007854

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