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Chromatin dynamics and the transcriptional competence of HSV-1 genomes during lytic infections

During latent infections with herpes simplex virus 1 (HSV-1), viral transcription is restricted and the genomes are mostly maintained in silenced chromatin, whereas in lytically infected cells all viral genes are transcribed and the genomes are dynamically chromatinized. Histones in the viral chroma...

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Detalles Bibliográficos
Autores principales: Hu, MiYao, Depledge, Daniel P., Flores Cortes, Esteban, Breuer, Judith, Schang, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855408/
https://www.ncbi.nlm.nih.gov/pubmed/31725813
http://dx.doi.org/10.1371/journal.ppat.1008076