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Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages

African swine fever (ASF) is a swine disease caused by a large, structurally complex, double-stranded DNA virus, African swine fever virus (ASFV). In domestic pigs, acute infection by highly virulent ASF viruses causes hemorrhagic fever and death. Previous work has suggested that ASFV pathogenesis i...

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Detalles Bibliográficos
Autores principales: Zhu, James J., Ramanathan, Palaniappan, Bishop, Elizabeth A., O’Donnell, Vivian, Gladue, Douglas P., Borca, Manuel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855437/
https://www.ncbi.nlm.nih.gov/pubmed/31725732
http://dx.doi.org/10.1371/journal.pone.0223955