Cargando…

Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages

African swine fever (ASF) is a swine disease caused by a large, structurally complex, double-stranded DNA virus, African swine fever virus (ASFV). In domestic pigs, acute infection by highly virulent ASF viruses causes hemorrhagic fever and death. Previous work has suggested that ASFV pathogenesis i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, James J., Ramanathan, Palaniappan, Bishop, Elizabeth A., O’Donnell, Vivian, Gladue, Douglas P., Borca, Manuel V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855437/ https://www.ncbi.nlm.nih.gov/pubmed/31725732 http://dx.doi.org/10.1371/journal.pone.0223955

Ejemplares similares

Full genome sequence for the African swine fever virus outbreak in the Dominican Republic in 1980
por: Spinard, Edward, et al.
Publicado: (2023)

Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine
por: Borca, Manuel V., et al.
Publicado: (2020)

Association of the Host Immune Response with Protection Using a Live Attenuated African Swine Fever Virus Model
por: Carlson, Jolene, et al.
Publicado: (2016)

Deletion of the H240R Gene in African Swine Fever Virus Partially Reduces Virus Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

Differential Effect of the Deletion of African Swine Fever Virus Virulence-Associated Genes in the Induction of Attenuation of the Highly Virulent Georgia Strain
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2019)

The C962R ORF of African Swine Fever Strain Georgia Is Non-Essential and Not Required for Virulence in Swine
por: Ramirez-Medina, Elizabeth., et al.
Publicado: (2020)

Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2020)

Early protection events in swine immunized with an experimental live attenuated classical swine fever marker vaccine, FlagT4G
por: Holinka, Lauren G., et al.
Publicado: (2017)

A Highly Effective African Swine Fever Virus Vaccine Elicits a Memory T Cell Response in Vaccinated Swine
por: Attreed, Sarah E., et al.
Publicado: (2022)

Evaluation in Swine of a Recombinant Georgia 2010 African Swine Fever Virus Lacking the I8L Gene
por: Vuono, Elizabeth, et al.
Publicado: (2020)

Experimental Infection of Domestic Pigs with an African Swine Fever Virus Field Strain Isolated in 2021 from the Dominican Republic
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

X69R Is a Non-Essential Gene That, When Deleted from African Swine Fever, Does Not Affect Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2020)

The 2022 Outbreaks of African Swine Fever Virus Demonstrate the First Report of Genotype II in Ghana
por: Spinard, Edward, et al.
Publicado: (2023)

CRISPR-Cas9, a tool to efficiently increase the development of recombinant African swine fever viruses
por: Borca, Manuel V., et al.
Publicado: (2018)

Complete Structural Predictions of the Proteome of African Swine Fever Virus Strain Georgia 2007
por: Spinard, Edward, et al.
Publicado: (2022)

Serum Neutralizing and Enhancing Effects on African Swine Fever Virus Infectivity in Adherent Pig PBMC
por: Canter, Jessica A., et al.
Publicado: (2022)

African swine fever virus evasion of host defences
por: Dixon, L.K., et al.
Publicado: (2019)

Development of a fluorescent ASFV strain that retains the ability to cause disease in swine
por: Borca, Manuel V., et al.
Publicado: (2017)

Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine
por: Gladue, Douglas P., et al.
Publicado: (2020)

Comparative Pathology and Pathogenesis of African Swine Fever Infection in Swine
por: Salguero, Francisco J.
Publicado: (2020)

African Swine Fever Vaccine Candidate ASFV-G-ΔI177L Produced in the Swine Macrophage-Derived Cell Line IPKM Remains Genetically Stable and Protective against Homologous Virulent Challenge
por: Borca, Manuel V., et al.
Publicado: (2023)

Development and In Vivo Evaluation of a MGF110-1L Deletion Mutant in African Swine Fever Strain Georgia
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2021)

Identification of a Continuously Stable and Commercially Available Cell Line for the Identification of Infectious African Swine Fever Virus in Clinical Samples
por: Rai, Ayushi, et al.
Publicado: (2020)

Development Real-Time PCR Assays to Genetically Differentiate Vaccinated Pigs From Infected Pigs With the Eurasian Strain of African Swine Fever Virus
por: Velazquez-Salinas, Lauro, et al.
Publicado: (2021)

Regulation and Evasion of Host Immune Response by African Swine Fever Virus
por: Wu, Lei, et al.
Publicado: (2021)

Interaction of CSFV E2 Protein with Swine Host Factors as Detected by Yeast Two-Hybrid System
por: Gladue, Douglas P., et al.
Publicado: (2014)

Whole genome sequencing and phylogenetic analysis of African swine fever virus detected in a backyard pig in Mongolia, 2019
por: Hyeon, Ji-Yeon, et al.
Publicado: (2023)

Evaluation of the Deletion of the African Swine Fever Virus Gene O174L from the Genome of the Georgia Isolate
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

Swine Host Protein Coiled-Coil Domain-Containing 115 (CCDC115) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2 during Virus Replication
por: Vuono, Elizabeth A., et al.
Publicado: (2020)

Editorial: African Swine Fever
por: Sánchez-Vizcaíno, Jose Manuel, et al.
Publicado: (2021)

SERTA Domain Containing Protein 1 (SERTAD1) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2, Which Is Involved in Virus Virulence in Swine
por: Vuono, Elizabeth A., et al.
Publicado: (2020)

A Re-Evaluation of African Swine Fever Genotypes Based on p72 Sequences Reveals the Existence of Only Six Distinct p72 Groups
por: Spinard, Edward, et al.
Publicado: (2023)

The Isolation and Replication of African Swine Fever Virus in Primary Renal-Derived Swine Macrophages
por: Oh, Taehwan, et al.
Publicado: (2021)

Classical Swine Fever Virus Structural Glycoprotein E2 Interacts with Host Protein ACADM during the Virus Infectious Cycle
por: Vuono, Elizabeth, et al.
Publicado: (2023)

Deletion of African Swine Fever Virus Histone-like Protein, A104R from the Georgia Isolate Drastically Reduces Virus Virulence in Domestic Pigs
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

Interaction of Structural Glycoprotein E2 of Classical Swine Fever Virus with Protein Phosphatase 1 Catalytic Subunit Beta (PPP1CB)
por: Vuono, Elizabeth A., et al.
Publicado: (2019)

The MGF360-16R ORF of African Swine Fever Virus Strain Georgia Encodes for a Nonessential Gene That Interacts with Host Proteins SERTAD3 and SDCBP
por: Ramírez-Medina, Elizabeth, et al.
Publicado: (2020)

Transcriptome profiling in swine macrophages infected with African swine fever virus at single-cell resolution
por: Zheng, Yuxuan, et al.
Publicado: (2022)

ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever
por: Borca, Manuel V., et al.
Publicado: (2021)

Deletion of the EP296R Gene from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs
por: Vuono, Elizabeth A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mcab3641i2a16v80r13e845dhe